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Phenotypes Associated with This Genotype
Genotype
MGI:3760854
Allelic
Composition		 Cd79atm5.1Cgn/Cd79atm5.1Cgn
Ightm1.2Rsky/Igh+
Genetic
Background		 involves: 129 * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd79atm5.1Cgn mutation (0 available); any Cd79a mutation (26 available)
Ightm1.2Rsky mutation (0 available); any Igh mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal class switch recombination ( J:125719 )
• increased percentage of B cells expressing IgG1 in the bone marrow and spleen compared to mutant mice with a wild-type Igalpha allele

immune system
abnormal class switch recombination ( J:125719 )
• increased percentage of B cells expressing IgG1 in the bone marrow and spleen compared to mutant mice with a wild-type Igalpha allele

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory