Phenotypes for Cd22 MGI:3760846 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Cd22^tm1Lam/Cd22^tm1Lam
Genetic Background	involves: 129 * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd22^tm1Lam mutation (1 available); any Cd22 mutation (63 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased mature B cell number ( J:125719 )

• reduction of recirculating mature B cells in the bone marrow

• reduced by 20%

abnormal B cell activation ( J:125719 )

• enhanced Ca²⁺ mobilization upon activation of B cells

hematopoietic system

decreased mature B cell number ( J:125719 )

• reduction of recirculating mature B cells in the bone marrow

• reduced by 20%

abnormal B cell activation ( J:125719 )

• enhanced Ca²⁺ mobilization upon activation of B cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23