Phenotypes Associated with This Genotype

Genotype
MGI:3760802

• Allelic Composition: Runx1^tm1Yg/Runx1^tm2Spe
• Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * ICR) or (involves: 129/Sv * MF1)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:125830 )

• mice die between E11.5 and E12.5 of hemorrhages in the central nervous system

cardiovascular system

internal hemorrhage ( J:125830 )

• mice die of hemorrhages in the central nervous system extensively in the fourth ventricle, ventral metencephalon and spinal cord

intracranial hemorrhage ( J:125830 )

spinal hemorrhage ( J:125830 )

nervous system

intracranial hemorrhage ( J:125830 )

spinal hemorrhage ( J:125830 )