Phenotypes Associated with This Genotype

Genotype
MGI:3760618

• Allelic Composition: Pstpip2^Lupo/Pstpip2^Lupo; Rag1^tm1Mom/Rag1^tm1Mom
• Genetic Background: involves: 129S7/SvEvBrd * C3HeB/FeJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

skin inflammation ( J:125785 )

• 88% of mice develop skin inflammation with a mean age of onset of 43+/-9 days compared to 98% (42.2+/-4 days) on a C3H background and 52% (124+/-92 days) on a C3H C57BL/6 background

• paw inflammation develops and is worse than in Pstpip2^Lupo homozygotes on a C3H C57BL/6 background

integument

skin inflammation ( J:125785 )

• 88% of mice develop skin inflammation with a mean age of onset of 43+/-9 days compared to 98% (42.2+/-4 days) on a C3H background and 52% (124+/-92 days) on a C3H C57BL/6 background

• paw inflammation develops and is worse than in Pstpip2^Lupo homozygotes on a C3H C57BL/6 background