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Phenotypes Associated with This Genotype
Genotype
MGI:3760163
Allelic
Composition		 Rr250409tm1Lky/Rr250409+
Genetic
Background		 involves: 129X1/SvJ * BALB/c * C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased interleukin-4 secretion ( J:125684 )
• after 4 days in culture, CD4+ T cells stimulated under TH2 conditions (phorbol 12-myristate 13-acetate and ionomycin) produce less IL-4 than wild-type cells but more than cells homozygous for the Cigs1tm1Lky allele

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory