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Phenotypes Associated with This Genotype
Genotype
MGI:3759463
Allelic
Composition		 Robo2tm1.1Rilm/Robo2+
Tg(Hoxb7-EGFP)33Cos/?
Genetic
Background		 involves: 129 * C57BL/6 * CBA * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Robo2tm1.1Rilm mutation (0 available); any Robo2 mutation (102 available)
Tg(Hoxb7-EGFP)33Cos mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
abnormal renal/urinary system morphology ( J:125214 )
• mice exhibit unilateral congenital anomalies of the kidney and urinary tract with vesicouretal reflux (CAKUT-VUR)
• mice exhibit uretrovesical junctions
dilated ureter ( J:125214 )
• mice display early ureter dilation
large ureter ( J:125214 )
• mice exhibit massive and lesser megaureter

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory