Phenotypes for Inhba Inhbb MGI:3758893 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Inhba^tm1Zuk/Inhba^tm3Zuk Inhbb^tm1Jae/Inhbb^tm1Jae
Genetic Background	involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Inhba^tm1Zuk mutation (2 available); any Inhba mutation (31 available)
Inhba^tm3Zuk mutation (1 available); any Inhba mutation (31 available)
Inhbb^tm1Jae mutation (3 available); any Inhbb mutation (24 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

female infertility ( J:125354 )

• 3 of 5 females are infertile

reduced female fertility ( J:125354 )

• the number of litters produced by females is reduced 43% (0.10+/-0.07 litters per month compared 0.89+/-0.04 litters per month in Inhba^tm1Zuk/Inhba^tm3Zuk mice)

• however, there is no difference in the number of oocytes produced upon superovulation compared to Inhba^tm1Zuk/Inhba^tm3Zuk females

decreased litter size ( J:125354 )

• the number of pups per litter is decreased 33% relative (1.00+/-0.63 pups per litter compared to 7.78+/-0.48 pups per litter in Inhba^tm1Zuk/Inhba^tm3Zuk mice)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23