Phenotypes for Lfng Ripply2 MGI:3758871 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Lfng^tm1Rjo/Lfng^tm1Rjo Ripply2^tm1.1Ysa/Ripply2^tm1.1Ysa
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6 * CBA * ICR

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lfng^tm1Rjo mutation (0 available); any Lfng mutation (34 available)
Ripply2^tm1.1Ysa mutation (1 available); any Ripply2 mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal rostral-caudal axis patterning ( J:123846 )

• embryos show a more rostralized phenotype than Ripply2-null embryos

skeleton

absent vertebral pedicles ( J:123846 )

• pedicals of the neural arches are almost completely absent

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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