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Phenotypes Associated with This Genotype
Genotype
MGI:3758748
Allelic
Composition
Notch1tm1Agt/Notch1tm1Agt
Tg(Tyr-cre)2Lru/0
Genetic
Background
involves: 129 * BALB/c * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Notch1tm1Agt mutation (0 available); any Notch1 mutation (115 available)
Tg(Tyr-cre)2Lru mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• dispersed gray hairs are observed, identical to Notch2 mutants or Notch1/Notch2 double heterozygotes, but first gray hairs are only visible at 12 weeks

integument
• dispersed gray hairs are observed, identical to Notch2 mutants or Notch1/Notch2 double heterozygotes, but first gray hairs are only visible at 12 weeks


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory