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Phenotypes Associated with This Genotype
Genotype
MGI:3758727
Allelic
Composition		 Dp(11Cops3-Rnf112)1Jrl/0
Rai1tm1Jrl/Rai1+
Genetic
Background		 involves: 129S/SvEvBrd * 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dp(11Cops3-Rnf112)1Jrl mutation (1 available); any Dp(11Cops3-Rnf112)1Jrl mutation (1 available)
Rai1tm1Jrl mutation (1 available); any Rai1 mutation (72 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
hyperactivity ( J:114996 )
• mice are more active than wild-type mice
• however, anxiety and defective learning and memory behaviors observed in either heterozygote are no longer present

growth/size/body
growth/size/body region phenotype ( J:114996 )
N
• mice have normal body weights unlike in either heterozygote

nervous system
nervous system phenotype ( J:114996 )
N
• unlike in Rai1tm1Jrl heterozygotes, there is no evidence of epileptic seizures

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory