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Phenotypes Associated with This Genotype
Genotype
MGI:3758000
Allelic
Composition		 Tg(Myh6-tTA)55Rbns/0
Tg(Myh6*/tetO-GCaMP2)1Mik/0
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Myh6*/tetO-GCaMP2)1Mik mutation (1 available)
Tg(Myh6-tTA)55Rbns mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
enlarged heart ( J:107637 )
• cardiomegaly develops in adults in the absence of dox (unregulated expression of GCaMP2); double transgenics maintained on dox have normal heart size

growth/size/body
enlarged heart ( J:107637 )
• cardiomegaly develops in adults in the absence of dox (unregulated expression of GCaMP2); double transgenics maintained on dox have normal heart size

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory