Analysis Tools
mortality/aging
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• newborn mice do not survive past postnatal day one
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nervous system
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• after E11.5, expression level of tyrosine hydroxylase brain is significantly lower relative to non-transgenic mice indicating loss of dopaminergic neurons during development
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respiratory system
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• homozygotes delivered by Caesarean section at 19 days post-coitum have an higher incidence of apneas after delivery compared to heterozygotes or wild-type littermates
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