Phenotypes Associated with This Genotype

Genotype
MGI:3723598

• Allelic Composition: Tax1bp1^{GT(RRJ464)Byg}/Tax1bp1^{GT(RRJ464)Byg}
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:124968 )

• beginning at E13.5 all embryos die from hemorrhaging and/or multiple cardiac defects

cardiovascular system

abnormal heart morphology ( J:124968 )

• at E13.5, mice exhibit multiple cardiac defects

hemorrhage ( J:124968 )

• at E13.5, mice exhibit hemorrhaging

cellular

abnormal cell physiology ( J:124968 )

• mouse embryonic fibroblasts grow poorly in culture