Phenotypes Associated with This Genotype

Genotype
MGI:3723464

• Allelic Composition: Omp^tm1(tTA)Gogo/Omp⁺; Tg(tetO-Kcnj2,lacZ)1Gogo/?
• Genetic Background: involves: 129 * C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal olfactory bulb morphology ( J:124299 )

• following doxycycline treatment, organization of the glomeruli in the dorsal part of the bulb remains disorganized, thinly innervated, necklace glomeruli are absent, and nerves that enter the bulb coalesce into a giant glomerulus-like structure

abnormal olfactory nerve morphology ( J:124299 )

• following doxycycline treatment, the spiking activity of olfactory nerves is inhibited

• following doxycycline treatment, the entry of the sensory neuron into the olfactory bulb is delayed