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Phenotypes Associated with This Genotype
Genotype
MGI:3723461
Allelic
Composition		 Atf4tm1Aki/Atf4tm1Aki
Tg(Cryaa-Atf4)4Aki/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atf4tm1Aki mutation (0 available); any Atf4 mutation (23 available)
Tg(Cryaa-Atf4)4Aki mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal lens fiber morphology ( J:56007 )
• hyperplasia of the lens secondary fibers, characterized by excessive elongation and winding of lens fibers, along with densely arranged fiber cell nuclei

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory