Analysis Tools
embryo
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• authors state that the defects similar to those seen in homozygous mice are present in heterozygotes when one parent is homozygous and the other heterozygous for the null allele
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reproductive system
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• maternal inheritance of the null allele is increased
• at E10.5, mice carrying a maternal copy of the null allele were more common than those carrying a maternal wild-type copy
• transmission rations of wild-type to null allele are 31% to 54% at E10.5 and 19% to 81% during ovulation
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