Analysis Tools
mortality/aging
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• fewer than expected embryos are born
• however, mice that are born are viable, fertile and show no obvious defects
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embryo
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• mice produced from null parents exhibit severe malformations including resorptions or loss of embryo structures and mild malformations including tail rotation defects, neural tube closure defects or superficial hemorrhaging
|
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• some mice have an open neural tube
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cardiovascular system
hemorrhage
(
J:124188
)
|
• some mice exhibit external hemorrhaging
|
limbs/digits/tail
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• some mice have tail defects such as a twisted tail
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nervous system
|
• some mice have an open neural tube
|
