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Phenotypes Associated with This Genotype
Genotype
MGI:3723282
Allelic
Composition		 Tg(BCR/ABL)623Hkp/?
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(BCR/ABL)623Hkp mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:76680 )
• average survival is 200 days

neoplasm
increased leukemia incidence ( J:76680 )
• develop B-lineage leukemia
increased B cell derived lymphoma incidence ( J:76680 )
• develop B-lineage lymphoma

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory