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Phenotypes Associated with This Genotype
Genotype
MGI:3722932
Allelic
Composition		 E2f3tm1.2Gle/E2f3tm1.2Gle
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
E2f3tm1.2Gle mutation (0 available); any E2f3 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, incomplete penetrance ( J:75726 )
• fewer than expected mice are born
• however, mice survive into adulthood and are fertile

cellular
abnormal cell physiology ( J:75726 )
• growth rate of mouse embryonic fibroblasts from E13.5 embryos is reduced
• adenovirus-Myc fails to induce S phase as it does in wild-type mouse embryonic fibroblasts

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory