Phenotypes for E2f1 E2f3 Rbl1 Tg(Pax6-cre,GFP)2Pgr MGI:3722927 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	E2f1^tm1Meg/E2f1^tm1Meg E2f3^tm1.1Gle/E2f3^tm1.1Gle Rbl1^tm1Htr/Rbl1^tm1Htr Tg(Pax6-cre,GFP)2Pgr/?
Genetic Background	involves: 129 * C57BL/6 * FVB/N * NMRI

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
E2f1^tm1Meg mutation (2 available); any E2f1 mutation (25 available)
E2f3^tm1.1Gle mutation (0 available); any E2f3 mutation (32 available)
Rbl1^tm1Htr mutation (0 available); any Rbl1 mutation (60 available)
Tg(Pax6-cre,GFP)2Pgr mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

vision/eye phenotype ( J:124204 )

N	• bipolar and ganglion cell death, starburst amacrine cell (SAC) differentiation, and SAC track disorder observed in Rbl1 null, Rbl1/E2f3 null or Rbl1/E2f1 null mice are rescued

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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