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Phenotypes Associated with This Genotype
Genotype
MGI:3722316
Allelic
Composition
Apoetm1Unc/Apoetm1Unc
Tg(APPV717I)1130Kha/0
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoetm1Unc mutation (35 available); any Apoe mutation (164 available)
Tg(APPV717I)1130Kha mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• absence of Apoe does not modify or improve mouse survival relative to Tg(APPV717I)1130Kha mice expressing Apoe; significant mortality before 150 days of age is observed


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory