About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3722314
Allelic
Composition
Dmdtm1Mok/Y
Genetic
Background
involves: 129S/SvEv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dmdtm1Mok mutation (2 available); any Dmd mutation (159 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
muscle
• at 4 and 4.5 months of age, the diaphragm exhibits an increase in connective tissue
• at 4 and 4.5 months of age, dissected muscles are whitish and hypertrophic
• several muscles exhibit an increase in size and an increase in connective tissue with necrotic fibers
• muscle degeneration is similar to that observed in other Dmd deficient mice

cellular
• in the plasma membrane of the extensor digitorum longus, caveola density is increased while the density of intramembranous particles is decreased

Mouse Models of Human Disease
OMIM ID Ref(s)
Muscular Dystrophy, Duchenne Type; DMD 310200 J:43164


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/17/2016
MGI 6.05
The Jackson Laboratory