About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3722314
Allelic
Composition
Dmdtm1Mok/Y
Genetic
Background
involves: 129S/SvEv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dmdtm1Mok mutation (2 available); any Dmd mutation (135 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
muscle
• at 4 and 4.5 months of age, the diaphragm exhibits an increase in connective tissue (J:43164)
• at 4 and 4.5 months of age, the diaphragm exhibits an increase in connective tissue (J:43164)
• at 4 and 4.5 months of age, dissected muscles are whitish and hypertrophic (J:43164)
• several muscles exhibit an increase in size and an increase in connective tissue with necrotic fibers (J:43164)
• muscle degeneration is similar to that observed in other Dmd deficient mice (J:43164)
• at 4 and 4.5 months of age, dissected muscles are whitish and hypertrophic (J:43164)
• several muscles exhibit an increase in size and an increase in connective tissue with necrotic fibers (J:43164)
• muscle degeneration is similar to that observed in other Dmd deficient mice (J:43164)

cellular
• in the plasma membrane of the extensor digitorum longus, caveola density is increased while the density of intramembranous particles is decreased (J:102549)
• in the plasma membrane of the extensor digitorum longus, caveola density is increased while the density of intramembranous particles is decreased (J:102549)

Mouse Models of Human Disease
OMIM ID Ref(s)
Muscular Dystrophy, Duchenne Type; DMD 310200 J:43164


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/02/2016
MGI 6.02
The Jackson Laboratory