Analysis Tools
nervous system
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• alpha motor neurons in the spinal cord anterior horn are decreased in number at 16 and 19 months
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behavior/neurological
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• latency to fall in a hanging testis reduced at 16 months of age
(J:83128)
• mice show a reduced rotarod performance and reached latency to fall after 18 seconds on day 200
(J:107901)
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• hindlimb and forelimb grip strength is reduced and 3 months and worsens at 16 months
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muscle
muscle spasm
(
J:83128
)
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• mice exhibit cramping when hung by their tails in which the whole body would start to tremble, then the forelimbs cramped, the neck stretched, the mouth opened and the tongue stuck out
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