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Phenotypes Associated with This Genotype
Genotype
MGI:3721555
Allelic
Composition
Cyp1atm1Dwn/Cyp1atm1Dwn
Tg(CYP1A1,CYP1A2)1Dwn/Tg(CYP1A1,CYP1A2)1Dwn
Genetic
Background
B6.Cg-Cyp1atm1Dwn Tg(CYP1A1,CYP1A2)1Dwn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cyp1atm1Dwn mutation (0 available); any Cyp1a mutation (0 available)
Tg(CYP1A1,CYP1A2)1Dwn mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
liver/biliary system
• after oral treatment with 125 mg/kg/day of benzo[a]pyrene BaP, mice show increased liver size

growth/size/body
• after oral treatment with 125 mg/kg/day of benzo[a]pyrene BaP, mice show increased liver size


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory