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Phenotypes Associated with This Genotype
Genotype
MGI:3721246
Allelic
Composition
Smobnb/Smobnb
Genetic
Background
involves: C3H/HeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smobnb mutation (0 available); any Smo mutation (40 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
embryo
• 13 of 25 mice initiate turning in the proper direction (to the right) while 12 of 25 mice start to turn in the opposite direction (to the left)
• at E9.5, limb buds are disproportionally large

cardiovascular system
• no clear looping to the left or right is observed
• at E9.5
• at E9.5, mice exhibit hemorrhages in the mesenchyme of the tail, limb buds and head

growth/size/body

limbs/digits/tail
• at E9.5, limb buds are disproportionally large

homeostasis/metabolism
• at E9.5


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory