Phenotypes for Atf2 Atf7 MGI:3721133 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Atf2^tm1Nicj/Atf2^tm1Nicj Atf7^tm1Nicj/Atf7^tm1Nicj
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atf2^tm1Nicj mutation (0 available); any Atf2 mutation (89 available)
Atf7^tm1Nicj mutation (0 available); any Atf7 mutation (61 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:123909 )

• pups die between E11.5 and E12.5

hematopoietic system

abnormal common myeloid progenitor cell morphology ( J:123909 )

• E12.5 myeloid and erythroid precursors from the liver form fewer hematopoeitic colonies compared to wild-type cells

anemia ( J:123909 )

• some pups recovered between E11.5 and E12.5 are anemic

embryo

embryonic growth arrest ( J:123909 )

• some pups recovered between E11.5 and E12.5 exhibit developmental arrest and death

embryonic growth retardation ( J:123909 )

• some pups recovered between E11.5 and E12.5 exhibit developmental growth retardation

growth/size/body

embryonic growth retardation ( J:123909 )

• some pups recovered between E11.5 and E12.5 exhibit developmental growth retardation

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23