About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3721104
Allelic
Composition		 F11tm1Gjb/F11tm1Gjb
Genetic
Background		 B6.129X1-F11tm1Gjb
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
F11tm1Gjb mutation (1 available); any F11 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased susceptibility to ischemic brain injury ( J:123758 )
• following transient cerebral ischemia, fibrin accumulation is less than in wild-type mice
• following transient cerebral ischemia, ischemic neurodegeneration associated with occlusions of vessel lumina is less severe than in wild-type mice and fewer occlusions are detected
decreased cerebral infarct size ( J:123758 )
• following transient cerebral ischemia, infarct size is reduced (27+/-24 mm3 compared to 46+/-21 mm3 in wild-type mice)

homeostasis/metabolism
decreased susceptibility to ischemic brain injury ( J:123758 )
• following transient cerebral ischemia, fibrin accumulation is less than in wild-type mice
• following transient cerebral ischemia, ischemic neurodegeneration associated with occlusions of vessel lumina is less severe than in wild-type mice and fewer occlusions are detected
decreased cerebral infarct size ( J:123758 )
• following transient cerebral ischemia, infarct size is reduced (27+/-24 mm3 compared to 46+/-21 mm3 in wild-type mice)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory