Phenotypes Associated with This Genotype

Genotype
MGI:3720885

• Allelic Composition: Ntf3^tm1Jae/Ntf3^tm1Jae
• Genetic Background: involves: 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

absent muscle spindles ( J:83461 )

• no muscle spindles are found in the soleus muscle during development and at later stages

abnormal dorsal root ganglion morphology ( J:83461 )

• 70% of dorsal root ganglia neurons are lost relative to in wild-type mice

absent proprioceptive neurons ( J:83461 )

• proprioceptive neurons are lost

muscle

absent muscle spindles ( J:83461 )

• no muscle spindles are found in the soleus muscle during development and at later stages