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Phenotypes Associated with This Genotype
Genotype
MGI:3720797
Allelic
Composition
Csnk2btm1.1Bb/Csnk2btm1.1Bb
Tg(ACTA1-cre)79Jme/?
Genetic
Background
involves: 129S2/SvPasCrl * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Csnk2btm1.1Bb mutation (0 available); any Csnk2b mutation (12 available)
Tg(ACTA1-cre)79Jme mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• after 4 months grip strength decreases as measured by the amount of time they could cling upside-down to a wire grid

nervous system
• at 6 months, mice exhibit an impaired morphological appearance of the synaptic cholinergic receptor clusters whereby clusters are spotty
• after 4 months, miniature endplate currents reduction accompanies reduction in grip strength

growth/size/body
• at 4 months, body weight is slightly reduced by 5% to 10%


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory