Phenotypes Associated with This Genotype

Genotype
MGI:3720681

• Allelic Composition: Lepr^KK/Lepr^KK
• Genetic Background: involves: C57BL/6J * KK/HlLt

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

increased body weight ( J:53637 )

• mice weight more than non-obese C57BLKS/J mice

obese ( J:53637 )

• mice are obese but not as obese as C57BLKS/J-Lepr^db mice

homeostasis/metabolism

increased circulating glucose level ( J:53637 )

increased circulating insulin level ( J:53637 )

increased circulating leptin level ( J:53637 )

• leptin levels are elevated 12-fold relative to normal levels in adipose tissue