Phenotypes for Fas Tg(Lck-cre)548Jxm MGI:3720606 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Fas^tm1Ach/Fas^tm1Ach Tg(Lck-cre)548Jxm/?
Genetic Background	involves: C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fas^tm1Ach mutation (0 available); any Fas mutation (83 available)
Tg(Lck-cre)548Jxm mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased double-positive T cell number ( J:123556 )

• CD3+B220+ double positive cells accumulate

increased anti-nuclear antigen antibody level ( J:123556 )

hematopoietic system

increased double-positive T cell number ( J:123556 )

• CD3+B220+ double positive cells accumulate

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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