Phenotypes Associated with This Genotype

Genotype
MGI:3720078

• Allelic Composition: Hba^b2(th)/Hba⁺
• Genetic Background: involves: 101/Rl * SEC/Rl

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

abnormal hemoglobin ( J:5686 )

• display a diminished fast band, higher than normal solubility, and precipitates containing few, large, found aggregates of crystals

increased erythrocyte clearance ( J:150481 )

• chromium labelled erythrocytes transplanted from heterozygous males into wild-type hosts have a half-life of only 10.3 days whereas that from normal donors into normal hosts is 12.7 days

• the calculated lifespan of transplanted heterozygous erythrocytes is shorter than of transplanted normal erythrocytes

mortality/aging

premature death ( J:150481 )

• the mean age of death is less than normal