Phenotypes Associated with This Genotype

Genotype
MGI:3719655

• Allelic Composition: Igk^tm1Dhu/Igk^tm1Dhu; Iglc1^tm1.1Ust/Iglc1^tm1.1Ust
• Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased B cell number ( J:68144 )

• lambda1 B cell numbers are reduced to 15.8% from 92.2% in Igl-C1^tm1Ust/ Igl-C1^tm1Ust Igk^tm1Dhu/ Igk^tm1Dhu mice

• lambda1 B cell numbers are lower than in wild-type mice (15.8% compared with 52.5% in wild-type mice)

hematopoietic system

decreased B cell number ( J:68144 )

• lambda1 B cell numbers are reduced to 15.8% from 92.2% in Igl-C1^tm1Ust/ Igl-C1^tm1Ust Igk^tm1Dhu/ Igk^tm1Dhu mice

• lambda1 B cell numbers are lower than in wild-type mice (15.8% compared with 52.5% in wild-type mice)