Mouse Genome Informatics
hm
    Xpctm1Ecf/Xpctm1Ecf
involves: 129 * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       

Lungs of Xpctm1Ecf/Xpctm1Ecf mice show a range of lesions

tumorigenesis
• lung tumors are seen as early as 6 months of age and by 16-17 months of age, all mutants develop tumors
• incidence and multiplicity of lung tumors increases with age
• most lung tumors are classified as adenomas, with only a few progressing to malignant carcinomas
• a few lung tumors progress to malignant carcinomas

Mouse Models of Human Disease
OMIM IDRef(s)
Lung Cancer 211980 J:101421