Phenotypes Associated with This Genotype

Genotype
MGI:3719108

• Allelic Composition: Hbb^tm1Tow/Hbb⁺
• Genetic Background: involves: 129S2/SvPas * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

enlarged spleen ( J:29087 )

• spleens are dramatically enlarged

increased spleen weight ( J:29087 )

• spleens weight is increased to 800mg compared to 80mg in wild-type mice

anemia ( J:29087 )

increased bone marrow cell number ( J:29087 )

decreased hemoglobin content ( J:29087 )

• hemoglobin levels are lower than in wild-type mice (7.1+/-0.5 g/dl compared to 14.9+/-0.7 g/dl

anisopoikilocytosis ( J:29087 )

reticulocytosis ( J:29087 )

immune system

enlarged spleen ( J:29087 )

• spleens are dramatically enlarged

increased spleen weight ( J:29087 )

• spleens weight is increased to 800mg compared to 80mg in wild-type mice

growth/size/body

enlarged spleen ( J:29087 )

• spleens are dramatically enlarged

increased spleen weight ( J:29087 )

• spleens weight is increased to 800mg compared to 80mg in wild-type mice