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Phenotypes Associated with This Genotype
Genotype
MGI:3719088
Allelic
Composition		 Sox9tm2.1Crm/Sox9tm2.1Crm
Genetic
Background		 involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox9tm2.1Crm mutation (0 available); any Sox9 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:89368 )
• mice die at E11.5 due to cardiac failure

reproductive system
abnormal primary sex determination ( J:89368 )
• no sex chords form in XY mice

cardiovascular system
congestive heart failure ( J:89368 )
• mice die at E11.5 due to cardiac failure

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory