Phenotypes Associated with This Genotype

Genotype
MGI:3718802

• Allelic Composition: En1^tm1Alj/En1^tm1Alj; Wnt7a^tm1Amc/Wnt7a^tm1Amc; Tg(Wnt1-En1)1Amc/0
• Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:45301 )

• viability ranged from 3 weeks to beyond 4 months

perinatal lethality, incomplete penetrance ( J:45301 )

• born in lower numbers than expected

limbs/digits/tail

abnormal autopod morphology ( J:45301 )

• ventral surface of autopods is pigmented

abnormal digit morphology ( J:45301 )

• dorsal sesamoid processes in the 3rd digit

• no polydactyly

oligodactyly ( J:45301 )

• some mice lack digit 5

abnormal foot pad morphology ( J:45301 )

• ectopic foot pads on digits 2, 3, and 4

• striations on the tips of digits 2, 3, and 5

• hardened foot pads

abnormal forelimb morphology ( J:45301 )

• dorsal surface of forelimbs with ventral surface characteristics