Phenotypes Associated with This Genotype

Genotype
MGI:3718801

• Allelic Composition: En1^tm1Alj/En1^tm1Alj; Tg(Wnt1-En1)1Amc/0
• Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality ( J:45301 )

• perinatal brain lethality is rescued

nervous system

abnormal brain morphology ( J:45301 )

• brain abnormalities rescued

limbs/digits/tail

abnormal digit morphology ( J:45301 )

• ectopic hair growth on the ventral surface of the anterior digits

• related to ectopic ventral expression of Lmx-1B

abnormal foot pad morphology ( J:45301 )

• dorsal foot pads at the distal tips of digits 2 and 3 in 3 of 7 mice