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Phenotypes Associated with This Genotype
Genotype
MGI:3718239
Allelic
Composition
Hoxd11tm1Ipc/Hoxd11tm2Ddu
Genetic
Background
involves: 129S2/SvPas * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxd11tm1Ipc mutation (0 available); any Hoxd11 mutation (14 available)
Hoxd11tm2Ddu mutation (0 available); any Hoxd11 mutation (14 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
skeleton
• 7 of 7 mice have carpal bone defects
• cartilage and ossification centers between the pyramidal and navicular-lunate are partially fused
• 3 of 7 mice have an abnormal L6
• 2 of 7 mice showed an L7 formula instead of an L6 formula found in wild-type mice

limbs/digits/tail
• 7 of 7 mice have carpal bone defects
• cartilage and ossification centers between the pyramidal and navicular-lunate are partially fused


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory