Phenotypes Associated with This Genotype

Genotype
MGI:3718238

• Allelic Composition: Del(2Hoxd11-Hoxd13)29Ddu/Del(2Hoxd11-Hoxd13)29Ddu; Hoxd11^tm1Ipc/Hoxd11^tm1Ipc
• Genetic Background: involves: 129S2/SvPas * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

abnormal carpal bone morphology ( J:41828 )

• 3 of 3 mice have carpal bone defects

fused carpal bones ( J:41828 )

• proximal carpal elements are fused in some mice

abnormal lumbar vertebrae morphology ( J:41828 )

• 3 of 3 mice have abnormal L4

increased lumbar vertebrae number ( J:41828 )

• 3 of 3 mice have abnormal L7 formula instead of an L6 formula found in wild-type mice

limbs/digits/tail

abnormal carpal bone morphology ( J:41828 )

• 3 of 3 mice have carpal bone defects

fused carpal bones ( J:41828 )

• proximal carpal elements are fused in some mice

abnormal digit morphology ( J:41828 )

• the second phalanges of digits II and V is completely lost

• other digits have phalanges defects