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Phenotypes Associated with This Genotype
Genotype
MGI:3718002
Allelic
Composition		 Cdc25atm1Kiyo/Cdc25a+
Tg(MMTV-vHaras)SH1Led/?
Genetic
Background		 involves: 129/Sv * C57BL/6 * C57BL/6J * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdc25atm1Kiyo mutation (0 available); any Cdc25a mutation (34 available)
Tg(MMTV-vHaras)SH1Led mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
decreased incidence of induced tumors ( J:123144 )
• mice develop mammary and salivary tumors with a latency of 60 weeks compared to 18 weeks in Tg(MMTV-vHaras)SH1Led transgenic mice
• 10% of mice do not develop tumors within 2 years of observation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory