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Phenotypes Associated with This Genotype
Genotype
MGI:3717875
Allelic
Composition		 Trp53tm1Brd/Trp53tm1Brd
Tg(KRT14-rtTA)208Jek/Y
Tg(tetO-KLF4)32831Rup/0
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6NTac * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(KRT14-rtTA)208Jek mutation (1 available)
Tg(tetO-KLF4)32831Rup mutation (1 available)
Trp53tm1Brd mutation (5 available); any Trp53 mutation (232 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
abnormal skin morphology ( J:96886 )
• male animals exhibit epithelial dysplasia associated with infiltration of the dermis by well-vascularized, cellular or fibrotic stroma, or a fibrovascular response upon induction by doxycycline

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory