Phenotypes Associated with This Genotype

Genotype
MGI:3717735

• Allelic Composition: Foxf2^W174R/Foxf2^W174R
• Genetic Background: involves: BALB/c * C3H/HeH

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Foxf2^W174R/Foxf2^W174R pups are smaller at 3 days after birth and consume less milk at birth

mortality/aging

postnatal lethality, complete penetrance ( J:178103 )

• mice die within 14 days of birth

vision/eye

absent ciliary body ( J:178103 )

• formation of the ciliary body is absent in the E18.5 eye

abnormal eye development ( J:178103 )

• at E18.5, mice fail to exhibit evagination of tissue from the anterior optic cup unlike in wild-type mice

growth/size/body

decreased body size ( J:178103 )

• by P3

postnatal growth retardation ( J:178103 )

• mice fail to thrive after birth

craniofacial

craniofacial phenotype ( J:178103 )

N • mice exhibit normal primary and secondary palate