Phenotypes Associated with This Genotype

Genotype
MGI:3717128

• Allelic Composition: Zfp950^{Gt(ROSA)76Sor}/Zfp950^{Gt(ROSA)76Sor}; Arid5b^{Gt(ROSA)75Sor}/Arid5b^{Gt(ROSA)75Sor}
• Genetic Background: involves: 129S4/SvJaeSor

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:117491 )

• mice die within hours of birth

skeleton

abnormal skeleton morphology ( J:117491 )

• skeletal defects are more severe than in single transgenic

absent palatine bone horizontal plate ( J:117491 )

• near-absence of the palatin process in 4 of 5 mice

craniofacial

absent palatine bone horizontal plate ( J:117491 )

• near-absence of the palatin process in 4 of 5 mice

cleft palate ( J:117491 )

• partial or full cleft

digestive/alimentary system

absent palatine bone horizontal plate ( J:117491 )

• near-absence of the palatin process in 4 of 5 mice

cleft palate ( J:117491 )

• partial or full cleft

growth/size/body

absent palatine bone horizontal plate ( J:117491 )

• near-absence of the palatin process in 4 of 5 mice

cleft palate ( J:117491 )

• partial or full cleft