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Phenotypes Associated with This Genotype
Genotype
MGI:3717084
Allelic
Composition		 Trp53tm1Att/Trp53tm1Att
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trp53tm1Att mutation (1 available); any Trp53 mutation (232 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell cycle ( J:96433 )
• similar to Trp53 null cells, the percentage of cells in S phase is increased compared to wild-type cells
abnormal cell death ( J:96433 )
• in the absence of cre, MEFs are refractory to stress-induced cell death

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory