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Phenotypes Associated with This Genotype
Genotype
MGI:3716874
Allelic
Composition		 Clec7atm1Yiw/Clec7atm1Yiw
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Clec7atm1Yiw mutation (1 available); any Clec7a mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:122394 )
N
• treatment of bone marrow derived dendritic cells with zymosan does not really affect production of Il-6, Il-12, and TNF
abnormal dendritic cell physiology ( J:122394 )
• after stimulation with NaClO-oxidized zymosan, cytokine responses are abolished in bone marrow-derived dendritic cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory