Phenotypes Associated with This Genotype

Genotype
MGI:3716755

• Allelic Composition: Itpr1^m1Asb/Itpr1^m1Asb
• Genetic Background: involves: 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:122793 )

• without weaning, affected mice survive about 4 weeks after onset of symptoms

behavior/neurological

abnormal involuntary movement ( J:122793 )

• mice display paroxysmal movement disorder, often induced by touch

• abnormal movements occur predominantly below cervical level, and appear progressive

• phenotype presents at postnatal day 14