Phenotypes for Mesp2 Psen1 MGI:3715289 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Mesp2^{tm5(Notch1)Ysa}/Mesp2^{tm5(Notch1)Ysa} Psen1^tm1Shs/Psen1^tm1Shs
Genetic Background	involves: C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mesp2^{tm5(Notch1)Ysa} mutation (1 available); any Mesp2 mutation (30 available)
Psen1^tm1Shs mutation (0 available); any Psen1 mutation (57 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal vertebral arch morphology ( J:78989 )

• the metameric appearance of the axial skeleton is partially restored compared to Psen1^tm1Hko homozygotes

• ossicification centers of the pedicles are not completely fused and are irregularly segmented

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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