Phenotypes for Itgb1 Tg(RIP1-Tag)2Dh MGI:3715015 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Itgb1^tm1Ref/Itgb1^tm1Ref Tg(RIP1-Tag)2Dh/?
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgb1^tm1Ref mutation (0 available); any Itgb1 mutation (59 available)
Tg(RIP1-Tag)2Dh mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

abnormal tumor morphology ( J:122649 )

• 7.7% of mice have an increase in the number of disseminated tumor cell emboli within lymphatic vessels near tumors

• however, no metastasis is detected in mice with tumors

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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