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Phenotypes Associated with This Genotype
Genotype
MGI:3715010
Allelic
Composition		 Itgb1tm1Ref/Itgb1tm1Ref
Tg(Ins2-cre)1Heed/?
Genetic
Background		 involves: 129 * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgb1tm1Ref mutation (0 available); any Itgb1 mutation (59 available)
Tg(Ins2-cre)1Heed mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
increased pancreatic alpha cell number ( J:122649 )
• alpha cells are increased in number
disorganized pancreatic islets ( J:122649 )
• 81% of mice have alpha cells in the center of the islet

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory